genital wart treatments

Subject: Genital Wart Treatment
Description: genital wart treatment for condyloma caused by sexually transmitted disease hpv virus
Category: Sexually Transmitted Diseases

genital wart treatments

Background: Infections due to papillomaviruses are common and lead to a wide variety of clinical manifestations involving the epidermal surfaces.

Manifestations include common warts (verrucae vulgaris) , palmo-plantar warts, flat warts (verrucae plana) plana) genital wart treatments , oral warts, focal epithelia hyperplasia, epidermodysplasia verruciformis (EDV) , genital warts (condyloma acuminata) , Bowen papulosis, Bowen disease, papillomas of the mucosal surfaces, and intraepithelial neoplasias.

Very strong evidence indicates that certain certain papillomaviruses genital wart treatments are involved in cervical and genital cancers.

Pathophysiology: Papillomaviruses are small (55 nm) , double-stranded DNA viruses.

Over 200 genotypes of papillomaviruses infect the skin and mucosal surfaces.

These viruses are genital wart treatments are highly species specific.

More than 70 genotypes are known to infect humans.

Papillomaviruses have never been cultured in vitro but have been characterized by molecular methods.

These viruses are classified by the molecular molecular similarity of their genetic material and genital wart treatments are assigned a genotype number.

The viruses infect the basal keratinocyte of the epidermis, presumably through disruptions of the skin or mucosal surface.

At this location, location, genital wart treatments the virus remains latent in the cell as a circular episome.

As the epidermal cells differentiate and migrate to the surface, the virus is triggered to undergo replication and maturation.

The process of of virus replication alters genital wart treatments the character of the epidermis, resulting in cutaneous or mucosal excrescences known as warts.

Human papillomaviruses (HPVs) are grouped broadly into cutaneous and mucosal types, based on the clinical clinical location of genital wart treatments the lesion.

Although some overlap exists, most papillomaviruses have distinct anatomic predilections, infecting only certain epidermal sites, such as skin or genital mucosa.

A number of genotypes of virus have the genital wart treatments the potential to transform cells and are associated with epidermal malignancies.

The mechanism for transformation is not known, but viral DNA apparently integrates into the genome of the host cell.

Table 1.

Association Association of HPV Types with Morphology and Site of Skin Lesions genital wart treatments

Lesion Location HPV Genotype

Common wart Mostly hands 2, 4

Plantar wart Bottom of feet 1

Mosaic wart Hands and feet 2

Flat wart Arms, face, knees 3, knees 3, 10, 28, 41 genital wart treatments

Butcher wart Hand 7

Extragenital Bowen disease Upper and lower extremities, head 2, 3, 5, 16, 18, 20, 31, 33, 34, 54, 56, 58, 61, 62, 73

Macular plaques of epidermodysplasia epidermodysplasia verruciformis Light-exposed areas 5, 8, 9, 12, 14, 15, 17, 19, 20, 21, 22, 23, 24, 25, 36, 47, 50 genital wart treatments

Table 2.

HPV Types Associated with Anogenital Lesions

Lesions HPV Genotype

Genital warts 6, warts 6, 11 genital wart treatments

Flat condylomata 6, 11, 16, 18, 31

Cervical intraepithelial neoplasia 16, 18, 31, 33, 35, 39, 42, 43, 44, 45, 51, 52, 56

Bowen disease 6, 11

Buschke-Löwenstein tumors 6, 11

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By Burt Lidenwald